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Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role. We adapted a CRISPR‐based proteomics approach to identify novel factors associated with var genes in their natural chro...
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| Publicado no: | Mol Syst Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7440042/ https://ncbi.nlm.nih.gov/pubmed/32816370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209569 |
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