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Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role. We adapted a CRISPR‐based proteomics approach to identify novel factors associated with var genes in their natural chro...
Shranjeno v:
| izdano v: | Mol Syst Biol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7440042/ https://ncbi.nlm.nih.gov/pubmed/32816370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209569 |
| Oznake: |
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