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A Genome-Wide CRISPR/Cas9 Screen Reveals that Riboflavin Regulates Hydrogen Peroxide Entry into HAP1 Cells
Extracellular hydrogen peroxide can induce oxidative stress, which can cause cell death if unresolved. However, the cellular mediators of H(2)O(2)-induced cell death are unknown. We determined that H(2)O(2)-induced cytotoxicity is an iron-dependent process in HAP1 cells and conducted a CRISPR/Cas9-b...
Shranjeno v:
| izdano v: | mBio |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7439486/ https://ncbi.nlm.nih.gov/pubmed/32788383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01704-20 |
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