CCND1 Amplification Contributes to Immunosuppression and Is Associated With a Poor Prognosis to Immune Checkpoint Inhibitors in Solid Tumors

Cyclin D1 (CCND1) amplification relevant to malignant biological behavior exists in solid tumors. The prevalence and utility of CCND1 amplification as a biomarker for the clinical response to treatment with immune checkpoint inhibitors (ICIs) are unknown. Our study is a preliminary investigation mai...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Chen, Yu, Huang, Yingying, Gao, Xuan, Li, Yi, Lin, Jing, Chen, Lizhu, Chang, Lianpeng, Chen, Gang, Guan, Yanfang, Pan, Leong Kin, Xia, Xuefeng, Guo, Zengqing, Pan, Jianji, Xu, Yaping, Yi, Xin, Chen, Chuanben
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438829/
https://ncbi.nlm.nih.gov/pubmed/32903763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01620
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