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Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer

BACKGROUND: Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR, CCND1) target genes and prognostic gene alterations (MYC) had not been systematically studied. METHODS: To study het...

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Bibliografiska uppgifter
I publikationen:BMC Gastroenterol
Huvudupphovsmän: Stahl, Phillip, Seeschaaf, Carsten, Lebok, Patrick, Kutup, Asad, Bockhorn, Maximillian, Izbicki, Jakob R, Bokemeyer, Carsten, Simon, Ronald, Sauter, Guido, Marx, Andreas H
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324419/
https://ncbi.nlm.nih.gov/pubmed/25649416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0231-4
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