Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer

BACKGROUND: Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR, CCND1) target genes and prognostic gene alterations (MYC) had not been systematically studied. METHODS: To study het...

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Detalhes bibliográficos
Publicado no:BMC Gastroenterol
Main Authors: Stahl, Phillip, Seeschaaf, Carsten, Lebok, Patrick, Kutup, Asad, Bockhorn, Maximillian, Izbicki, Jakob R, Bokemeyer, Carsten, Simon, Ronald, Sauter, Guido, Marx, Andreas H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324419/
https://ncbi.nlm.nih.gov/pubmed/25649416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-015-0231-4
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