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Amplification and Expression of Cyclin D Genes (CCND1 CCND2 and CCND3) in Human Malignant Gliomas

Malignant gliomas frequently show genetic aberrations of genes coding for cell cycle regulatory proteins involved in the control of G1/S phase transition. These include mutation and/or deletion of the retinoblastoma (RB1) gene, homozygous deletion of the CDKN2A and CDKN2B genes, as well as amplifica...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Büschges, Rainer, Weber, Ruthild G., Actor, Bertrand, Lichter, Peter, Collins, V. Peter, Reifenberger, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098615/
https://ncbi.nlm.nih.gov/pubmed/10416984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.1999.tb00532.x
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