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Evaluation of CCND1 amplification and CyclinD1 expression: diffuse and strong staining of CyclinD1 could have same predictive roles as CCND1 amplification in ER positive breast cancers

CCND1 is amplified in around 10-20% of primary breast cancers and preferentially occurs in ER positive tumors. Though CCND1 amplification was reported predicting poor response of adjuvant tamoxifen treatment and poor prognosis in ER positive breast cancers, there were controversial data regarding th...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Zhishuang, Cui, Jingjing, Yu, Qiong, Wu, Xiaojuan, Pan, Aifeng, Li, Li
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759424/
https://ncbi.nlm.nih.gov/pubmed/27069548
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