Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors

Predictive biomarkers of response to immune checkpoint inhibitors (ICI) help to identify cancer patients who will benefit from immunotherapy. Protein kinase, DNA‐activated, catalytic subunit (PRKDC) is an important gene for DNA double‐strand break (DSB) repair and central T‐cell tolerance. We aimed...

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Foilsithe in:Mol Oncol
Main Authors: Chen, Yu, Li, Yi, Guan, Yanfang, Huang, Yingying, Lin, Jing, Chen, Lizhu, Li, Jin, Chen, Gang, Pan, Leong Kin, Xia, Xuefeng, Xu, Ning, Chang, Lianpeng, Guo, Zengqing, Pan, Jianji, Yi, Xin, Chen, Chuanben
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463346/
https://ncbi.nlm.nih.gov/pubmed/32502294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12739
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