Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors

Predictive biomarkers of response to immune checkpoint inhibitors (ICI) help to identify cancer patients who will benefit from immunotherapy. Protein kinase, DNA‐activated, catalytic subunit (PRKDC) is an important gene for DNA double‐strand break (DSB) repair and central T‐cell tolerance. We aimed...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Chen, Yu, Li, Yi, Guan, Yanfang, Huang, Yingying, Lin, Jing, Chen, Lizhu, Li, Jin, Chen, Gang, Pan, Leong Kin, Xia, Xuefeng, Xu, Ning, Chang, Lianpeng, Guo, Zengqing, Pan, Jianji, Yi, Xin, Chen, Chuanben
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463346/
https://ncbi.nlm.nih.gov/pubmed/32502294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12739
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