Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors

Predictive biomarkers of response to immune checkpoint inhibitors (ICI) help to identify cancer patients who will benefit from immunotherapy. Protein kinase, DNA‐activated, catalytic subunit (PRKDC) is an important gene for DNA double‐strand break (DSB) repair and central T‐cell tolerance. We aimed...

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Dades bibliogràfiques
Publicat a:Mol Oncol
Autors principals: Chen, Yu, Li, Yi, Guan, Yanfang, Huang, Yingying, Lin, Jing, Chen, Lizhu, Li, Jin, Chen, Gang, Pan, Leong Kin, Xia, Xuefeng, Xu, Ning, Chang, Lianpeng, Guo, Zengqing, Pan, Jianji, Yi, Xin, Chen, Chuanben
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463346/
https://ncbi.nlm.nih.gov/pubmed/32502294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12739
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