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Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors
Galantamine (GAL) and curcumin (CU) are alkaloids used to improve symptomatically neurodegenerative conditions like Alzheimer’s disease (AD). GAL acts mainly as an inhibitor of the enzyme acetylcholinesterase (AChE). CU binds to amyloid-beta (Aβ) oligomers and inhibits the formation of Aβ plaques. H...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7435983/ https://ncbi.nlm.nih.gov/pubmed/32717861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153341 |
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