Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

The inhibition of the enzyme acetylcholinesterase (AChE) increases the levels of the neurotransmitter acetylcholine and symptomatically improves the affected cognitive function. In the present study, we searched for novel AChE inhibitors by docking-based virtual screening of the standard lead-like s...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Doytchinova, Irini, Atanasova, Mariyana, Valkova, Iva, Stavrakov, Georgi, Philipova, Irena, Zhivkova, Zvetanka, Zheleva-Dimitrova, Dimitrina, Konstantinov, Spiro, Dimitrov, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010092/
https://ncbi.nlm.nih.gov/pubmed/29651876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1458031
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker