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Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database
The inhibition of the enzyme acetylcholinesterase (AChE) increases the levels of the neurotransmitter acetylcholine and symptomatically improves the affected cognitive function. In the present study, we searched for novel AChE inhibitors by docking-based virtual screening of the standard lead-like s...
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| Publicado no: | J Enzyme Inhib Med Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6010092/ https://ncbi.nlm.nih.gov/pubmed/29651876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1458031 |
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