Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

The inhibition of the enzyme acetylcholinesterase (AChE) increases the levels of the neurotransmitter acetylcholine and symptomatically improves the affected cognitive function. In the present study, we searched for novel AChE inhibitors by docking-based virtual screening of the standard lead-like s...

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Bibliografiska uppgifter
I publikationen:J Enzyme Inhib Med Chem
Huvudupphovsmän: Doytchinova, Irini, Atanasova, Mariyana, Valkova, Iva, Stavrakov, Georgi, Philipova, Irena, Zhivkova, Zvetanka, Zheleva-Dimitrova, Dimitrina, Konstantinov, Spiro, Dimitrov, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6010092/
https://ncbi.nlm.nih.gov/pubmed/29651876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2018.1458031
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