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Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
Disruption of protein:protein interactions (PPIs) that regulate the function of voltage-gated Na(+) (Nav) channels leads to neural circuitry aberrations that have been implicated in numerous channelopathies. One example of this pathophysiology is mediated by dysfunction of the PPI between Nav1.6 and...
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| Pubblicato in: | Molecules |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7435778/ https://ncbi.nlm.nih.gov/pubmed/32722255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153365 |
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