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Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Overexpressed EphB4 conduce to tumor development and is regarded as a potential anticancer target. Homoharringtonine (HHT) has been approved for hematologic malignancies treatment, but its effect on hepatocellular carcinoma (HCC) has not been studied. This study elucidated HHT could restrain the pro...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Zhu, Man, Gong, Zhengyan, Wu, Qing, Su, Qi, Yang, Tianfeng, Yu, Runze, Xu, Rui, Zhang, Yanmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429962/
https://ncbi.nlm.nih.gov/pubmed/32801343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02902-2
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