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Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Overexpressed EphB4 conduce to tumor development and is regarded as a potential anticancer target. Homoharringtonine (HHT) has been approved for hematologic malignancies treatment, but its effect on hepatocellular carcinoma (HCC) has not been studied. This study elucidated HHT could restrain the pro...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Zhu, Man, Gong, Zhengyan, Wu, Qing, Su, Qi, Yang, Tianfeng, Yu, Runze, Xu, Rui, Zhang, Yanmin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429962/
https://ncbi.nlm.nih.gov/pubmed/32801343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02902-2
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