Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression

Signaling proteins driving the proliferation of stem and progenitor cells are often encoded by proto-oncogenes. EphB receptors represent a rare exception; they promote cell proliferation in the intestinal epithelium and function as tumor suppressors by controlling cell migration and inhibiting invas...

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Main Authors: Genander, Maria, Halford, Michael M., Xu, Nan-Jie, Eriksson, Malin, Yu, Zuoren, Qiu, Zhaozhu, Martling, Anna, Greicius, Gedas, Chumley, Michael J., Zdunek, Sofia, Wang, Chenguang, Holm, Torbjörn, Goff, Stephen P., Pettersson, Sven, Pestell, Richard G., Henkemeyer, Mark, Frisén, Jonas
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786256/
https://ncbi.nlm.nih.gov/pubmed/19914164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.08.048
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