Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Overexpressed EphB4 conduce to tumor development and is regarded as a potential anticancer target. Homoharringtonine (HHT) has been approved for hematologic malignancies treatment, but its effect on hepatocellular carcinoma (HCC) has not been studied. This study elucidated HHT could restrain the pro...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Zhu, Man, Gong, Zhengyan, Wu, Qing, Su, Qi, Yang, Tianfeng, Yu, Runze, Xu, Rui, Zhang, Yanmin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429962/
https://ncbi.nlm.nih.gov/pubmed/32801343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02902-2
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