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Homoharringtonine suppresses tumor proliferation and migration by regulating EphB4-mediated β-catenin loss in hepatocellular carcinoma

Overexpressed EphB4 conduce to tumor development and is regarded as a potential anticancer target. Homoharringtonine (HHT) has been approved for hematologic malignancies treatment, but its effect on hepatocellular carcinoma (HCC) has not been studied. This study elucidated HHT could restrain the pro...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Death Dis
Κύριοι συγγραφείς: Zhu, Man, Gong, Zhengyan, Wu, Qing, Su, Qi, Yang, Tianfeng, Yu, Runze, Xu, Rui, Zhang, Yanmin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429962/
https://ncbi.nlm.nih.gov/pubmed/32801343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02902-2
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