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DiMSum: an error model and pipeline for analyzing deep mutational scanning data and diagnosing common experimental pathologies
Deep mutational scanning (DMS) enables multiplexed measurement of the effects of thousands of variants of proteins, RNAs, and regulatory elements. Here, we present a customizable pipeline, DiMSum, that represents an end-to-end solution for obtaining variant fitness and error estimates from raw seque...
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| Yayımlandı: | Genome Biol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429474/ https://ncbi.nlm.nih.gov/pubmed/32799905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02091-3 |
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