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Determining protein structures using deep mutagenesis

Determining the three-dimensional (3D) structures of macromolecules is a major goal of biological research because of the close relationship between structure and function but thousands of protein domains still have unknown structures. Structure determination usually relies on physical techniques in...

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Bibliografiske detaljer
Udgivet i:Nat Genet
Main Authors: Schmiedel, Jörn M., Lehner, Ben
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610650/
https://ncbi.nlm.nih.gov/pubmed/31209395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0431-x
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