A carregar...

Discovery of Novel Small Molecule Calcium Sensitizers for Cardiac Troponin C: A Combined Virtual and Experimental Screening Approach

Heart failure is a leading cause of death throughout the world and is triggered by a disruption of the cardiac contractile machinery. This machinery is regulated in a calcium-dependent manner by the protein complex troponin. Calcium binds to the N-terminal domain of cardiac troponin C (cNTnC) settin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Coldren, William H., Tikunova, Svetlana B., Davis, Jonathan P., Lindert, Steffen
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429331/
https://ncbi.nlm.nih.gov/pubmed/32633957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.0c00452
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!