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Structures reveal details of small molecule binding to cardiac troponin
In cardiac and skeletal muscle, the troponin complex turns muscle contraction on and off in a calcium-dependent manner. Many small molecules are known to bind to the troponin complex to modulate its calcium binding affinity, and this may be useful in a broad range of conditions in which striated mus...
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| Опубликовано в: : | J Mol Cell Cardiol |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391171/ https://ncbi.nlm.nih.gov/pubmed/27825981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.10.016 |
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