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Engineered Troponin C Constructs Correct Disease-related Cardiac Myofilament Calcium Sensitivity
Aberrant myofilament Ca(2+) sensitivity is commonly observed with multiple cardiac diseases, especially familial cardiomyopathies. Although the etiology of the cardiomyopathies remains unclear, improving cardiac muscle Ca(2+) sensitivity through either pharmacological or genetic approaches shows pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370186/ https://ncbi.nlm.nih.gov/pubmed/22511780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334953 |
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