Site-specific acetyl-mimetic modification of cardiac troponin I modulates myofilament relaxation and calcium sensitivity

OBJECTIVE: Cardiac troponin I (cTnI) is an essential physiological and pathological regulator of cardiac relaxation. Significant to this regulation, the post-translational modification of cTnI through phosphorylation functions as a key mechanism to accelerate myofibril relaxation. Similar to phospho...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Cell Cardiol
Main Authors: Lin, Ying H., Schmidt, William, Fritz, Kristofer S., Jeong, Mark Y., Cammarato, Anthony, Foster, D. Brian, Biesiadecki, Brandon J., McKinsey, Timothy A., Woulfe, Kathleen C.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363438/
https://ncbi.nlm.nih.gov/pubmed/31981571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2020.01.007
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items