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[(99m)Tc]Tc-DGA1, a Promising CCK(2)R-Antagonist-Based Tracer for Tumor Diagnosis with Single-Photon Emission Computed Tomography
Radiolabeled gastrin analogues have been proposed for theranostics of cholecystokinin subtype 2 receptor (CCK(2)R)-positive cancer. Peptide radioligands based on other receptor antagonists have displayed superior pharmacokinetics and higher biosafety than agonists. Here, we present DGA1, a derivativ...
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| Udgivet i: | Mol Pharm |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429258/ https://ncbi.nlm.nih.gov/pubmed/32568549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00605 |
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