[<sup>99m</sup>Tc]Tc-DB1 Mimics with Different-Length PEG Spacers: Preclinical Comparison in GRPR-Positive Models

<i>Background</i>: The frequent overexpression of gastrin-releasing peptide receptors (GRPRs) in human cancers provides the rationale for delivering clinically useful radionuclides to tumor sites using peptide carriers. Radiolabeled GRPR antagonists, besides being safer for human use, ha...

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Detaylı Bibliyografya
Asıl Yazarlar: Panagiotis Kanellopoulos, Emmanouil Lymperis, Aikaterini Kaloudi, Marion de Jong, Eric P. Krenning, Berthold A. Nock, Theodosia Maina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-07-01
Seri Bilgileri:Molecules
Konular:
gastrin-releasing peptide receptor targeting
[<sup>99m</sup>Tc]Tc-radiotracer
tumor targeting
[<sup>99m</sup>Tc]Tc-DB1 mimic
PEG<sub>x</sub>-spacer
neprilysin-inhibition
Online Erişim:https://www.mdpi.com/1420-3049/25/15/3418
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