[(99m)Tc]Tc-DB1 Mimics with Different-Length PEG Spacers: Preclinical Comparison in GRPR-Positive Models

Background: The frequent overexpression of gastrin-releasing peptide receptors (GRPRs) in human cancers provides the rationale for delivering clinically useful radionuclides to tumor sites using peptide carriers. Radiolabeled GRPR antagonists, besides being safer for human use, have often shown high...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kanellopoulos, Panagiotis, Lymperis, Emmanouil, Kaloudi, Aikaterini, de Jong, Marion, Krenning, Eric P., Nock, Berthold A., Maina, Theodosia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435657/
https://ncbi.nlm.nih.gov/pubmed/32731473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153418
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