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Enhanced Generation of Induced Cardiomyocytes Using a Small‐Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming
BACKGROUND: Given known inefficiencies in reprogramming of fibroblasts into mature induced cardiomyocytes (iCMs), we sought to identify small molecules that would overcome these barriers to cardiac cell transdifferentiation. METHODS AND RESULTS: We screened alternative combinations of compounds know...
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| Udgivet i: | J Am Heart Assoc |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429035/ https://ncbi.nlm.nih.gov/pubmed/32500803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015686 |
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