In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration

OBJECTIVE: The reprogramming of cardiac fibroblasts into induced cardiomyocyte-like cells improves ventricular function in myocardial infarction models. Only integrating persistent expression vectors have thus far been used to induce reprogramming, potentially limiting its clinical applicability. We...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Mathison, Megumi, Singh, Vivek P., Chiuchiolo, Maria J., Sanagasetti, Deepthi, Mao, Yun, Patel, Vivekkumar B., Yang, Jianchang, Kaminsky, Stephen M., Crystal, Ronald G., Rosengart, Todd K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297447/
https://ncbi.nlm.nih.gov/pubmed/27773576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2016.09.041
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