Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats

BACKGROUND: In spontaneously hypertensive rats (SHR) we observed profound myocardial metabolic changes during early hypertension before development of cardiac dysfunction and left ventricular hypertrophy. In this study, we evaluated whether metformin improved myocardial metabolic abnormalities and s...

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Bibliografski detalji
Izdano u:J Am Heart Assoc
Glavni autori: Li, Jie, Minćzuk, Krzysztof, Massey, James C., Howell, Nancy L., Roy, R. Jack, Paul, Soumen, Patrie, James T., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Brief Communication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428616/
https://ncbi.nlm.nih.gov/pubmed/32248762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015154
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