Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

BACKGROUND: Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and com...

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Publicado en:J Am Heart Assoc
Autores principales: Li, Jie, Kemp, Brandon A., Howell, Nancy L., Massey, James, Mińczuk, Krzysztof, Huang, Qiao, Chordia, Mahendra D., Roy, R. Jack, Patrie, James T., Davogustto, Giovanni E., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405673/
https://ncbi.nlm.nih.gov/pubmed/30764689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010926
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