Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

BACKGROUND: Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and com...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Main Authors: Li, Jie, Kemp, Brandon A., Howell, Nancy L., Massey, James, Mińczuk, Krzysztof, Huang, Qiao, Chordia, Mahendra D., Roy, R. Jack, Patrie, James T., Davogustto, Giovanni E., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405673/
https://ncbi.nlm.nih.gov/pubmed/30764689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010926
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