Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy

BACKGROUND: Sustained pressure overload leads to changes in cardiac metabolism, function, and structure. Both time course and causal relationships between these changes are not fully understood. Therefore, we studied spontaneously hypertensive rats (SHR) during early hypertension development and com...

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Bibliografiska uppgifter
I publikationen:J Am Heart Assoc
Huvudupphovsmän: Li, Jie, Kemp, Brandon A., Howell, Nancy L., Massey, James, Mińczuk, Krzysztof, Huang, Qiao, Chordia, Mahendra D., Roy, R. Jack, Patrie, James T., Davogustto, Giovanni E., Kramer, Christopher M., Epstein, Frederick H., Carey, Robert M., Taegtmeyer, Heinrich, Keller, Susanna R., Kundu, Bijoy K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405673/
https://ncbi.nlm.nih.gov/pubmed/30764689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010926
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