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Quantitative Positron Emission Tomography Imaging Detects Early Metabolic Remodeling in a Mouse Model of Pressure Overload Left Ventricular Hypertrophy in vivo

We proposed that metabolic remodeling in the form of increased myocardial glucose analogue 2-[(18)F] fluoro-2deoxy-D-glucose (FDG) uptake precedes and triggers the onset of severe contractile dysfunction in pressure overload left ventricular hypertrophy (LVH) in vivo. To test this hypothesis we used...

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Detalhes bibliográficos
Main Authors: Zhong, Min, Alonso, Clayton E., Taegtmeyer, Heinrich, Kundu, Bijoy K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727159/
https://ncbi.nlm.nih.gov/pubmed/23426760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.108092
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