Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function

Coordinated changes in signaling pathways and gene expression in hearts subjected to prolonged stress maintain cardiac function. Loss of steroid receptor coactivator-2 (SRC-2) results in a reversal to the fetal gene program and disrupts the response to pressure overload, accompanied by prominent eff...

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Udgivet i:FASEB J
Main Authors: Nam, Deok Hwa, Kim, Eunah, Benham, Ashley, Park, Hye-Kyung, Soibam, Benjamin, Taffet, George E., Kaelber, Jason T., Suh, Ji Ho, Taegtmeyer, Heinrich, Entman, Mark L., Reineke, Erin L.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355077/
https://ncbi.nlm.nih.gov/pubmed/30024790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800602R
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