Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function

Coordinated changes in signaling pathways and gene expression in hearts subjected to prolonged stress maintain cardiac function. Loss of steroid receptor coactivator-2 (SRC-2) results in a reversal to the fetal gene program and disrupts the response to pressure overload, accompanied by prominent eff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Nam, Deok Hwa, Kim, Eunah, Benham, Ashley, Park, Hye-Kyung, Soibam, Benjamin, Taffet, George E., Kaelber, Jason T., Suh, Ji Ho, Taegtmeyer, Heinrich, Entman, Mark L., Reineke, Erin L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355077/
https://ncbi.nlm.nih.gov/pubmed/30024790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800602R
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