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Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes
G protein–coupled receptors (GPCRs) are the largest and pharmaceutically most important class of membrane proteins encoded in the human genome, characterized by a seven-transmembrane helix architecture and a C-terminal amphipathic helix 8 (H8). In a minority of GPCR structures solved to date, H8 eit...
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| Опубликовано в: : | Sci Adv |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Association for the Advancement of Science
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7428336/ https://ncbi.nlm.nih.gov/pubmed/32851152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav8207 |
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