HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+) T cells

Seasonal influenza virus infections cause 290,000–650,000 deaths annually and severe morbidity in 3–5 million people. CD8(+) T-cell responses towards virus-derived peptide/human leukocyte antigen (HLA) complexes provide the broadest cross-reactive immunity against human influenza viruses. Several un...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O., Kedzierska, Katherine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428290/
https://ncbi.nlm.nih.gov/pubmed/32750095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008714
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