HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+) T cells

Seasonal influenza virus infections cause 290,000–650,000 deaths annually and severe morbidity in 3–5 million people. CD8(+) T-cell responses towards virus-derived peptide/human leukocyte antigen (HLA) complexes provide the broadest cross-reactive immunity against human influenza viruses. Several un...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O., Kedzierska, Katherine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2020
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428290/
https://ncbi.nlm.nih.gov/pubmed/32750095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008714
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