HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8(+) T cells

Seasonal influenza virus infections cause 290,000–650,000 deaths annually and severe morbidity in 3–5 million people. CD8(+) T-cell responses towards virus-derived peptide/human leukocyte antigen (HLA) complexes provide the broadest cross-reactive immunity against human influenza viruses. Several un...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Sant, Sneha, Quiñones-Parra, Sergio M., Koutsakos, Marios, Grant, Emma J., Loudovaris, Thomas, Mannering, Stuart I., Crowe, Jane, van de Sandt, Carolien E., Rimmelzwaan, Guus F., Rossjohn, Jamie, Gras, Stephanie, Loh, Liyen, Nguyen, Thi H. O., Kedzierska, Katherine
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428290/
https://ncbi.nlm.nih.gov/pubmed/32750095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008714
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