Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4(+) T cells post peptide loading

Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an array of immunomodulatory proteins including the B22 family, which has homologs in all patho...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Forsyth, Katherine S., Roy, Nathan H., Peauroi, Elise, DeHaven, Brian C., Wold, Erik D., Hersperger, Adam R., Burkhardt, Janis K., Eisenlohr, Laurence C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425992/
https://ncbi.nlm.nih.gov/pubmed/32745153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008685
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