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Epithelial Immunization Induces Polyfunctional CD8(+) T Cells and Optimal Mousepox Protection

We assessed several routes of immunization with vaccinia virus (VACV) in protecting mice against ectromelia virus (ECTV). By a wide margin, skin scarification provided the greatest protection. Humoral immunity and resident-memory T cells notwithstanding, several approaches revealed that circulating,...

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Detalhes bibliográficos
Main Authors: Hersperger, Adam R., Siciliano, Nicholas A., DeHaven, Brian C., Snook, Adam E., Eisenlohr, Laurence C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136261/
https://ncbi.nlm.nih.gov/pubmed/24899206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01464-14
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