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Defective Human Immunodeficiency Virus-Specific CD8(+) T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

Identifying the functions of human immunodeficiency virus (HIV)-specific CD8(+) T cells that are not merely modulated by the level of virus but clearly distinguish patients with immune control from those without such control is of paramount importance. Features of the HIV-specific CD8(+) T-cell resp...

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Autors principals: Migueles, Stephen A., Weeks, Kristin A., Nou, Eric, Berkley, Amy M., Rood, Julia E., Osborne, Christine M., Hallahan, Claire W., Cogliano-Shutta, Nancy A., Metcalf, Julia A., McLaughlin, Mary, Kwan, Richard, Mican, JoAnn M., Davey, Richard T., Connors, Mark
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772718/
https://ncbi.nlm.nih.gov/pubmed/19726501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01153-09
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