Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles

If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over HIV replication remains essential. Increased cytotoxic capacity of HIV-specific CD8(+) T-cells associated with efficient elimination of HIV-inf...

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Main Authors: Migueles, Stephen A., Rood, Julia E., Berkley, Amy M., Guo, Tiffany, Mendoza, Daniel, Patamawenu, Andy, Hallahan, Claire W., Cogliano, Nancy A., Frahm, Nicole, Duerr, Ann, McElrath, M. Juliana, Connors, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044701/
https://ncbi.nlm.nih.gov/pubmed/21383976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002002
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