Trivalent Adenovirus Type 5 HIV Recombinant Vaccine Primes for Modest Cytotoxic Capacity That Is Greatest in Humans with Protective HLA Class I Alleles

If future HIV vaccine design strategies are to succeed, improved understanding of the mechanisms underlying protection from infection or immune control over HIV replication remains essential. Increased cytotoxic capacity of HIV-specific CD8(+) T-cells associated with efficient elimination of HIV-inf...

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Autori principali: Migueles, Stephen A., Rood, Julia E., Berkley, Amy M., Guo, Tiffany, Mendoza, Daniel, Patamawenu, Andy, Hallahan, Claire W., Cogliano, Nancy A., Frahm, Nicole, Duerr, Ann, McElrath, M. Juliana, Connors, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044701/
https://ncbi.nlm.nih.gov/pubmed/21383976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002002
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