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Changes in Paracrine Interleukin-2 Requirement, CCR7 Expression, Frequency, and Cytokine Secretion of Human Immunodeficiency Virus-Specific CD4(+) T Cells Are a Consequence of Antigen Load

Virus-specific CD4(+) T-cell responses are thought to be required for the induction and maintenance of many effective CD8(+) T-cell and B-cell immune responses in experimental animals and humans. Although the presence of human immunodeficiency virus (HIV)-specific CD4(+) T cells has been documented...

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Detalhes bibliográficos
Main Authors: Tilton, John C., Luskin, Marlise R., Johnson, Alison J., Manion, Maura, Hallahan, Claire W., Metcalf, Julia A., McLaughlin, Mary, Davey, Richard T., Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865970/
https://ncbi.nlm.nih.gov/pubmed/17182676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01830-06
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