Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4(+) T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

Virus-specific CD4(+) T-cell function is thought to play a central role in induction and maintenance of effective CD8(+) T-cell responses in experimental animals or humans. However, the reasons that diminished proliferation of human immunodeficiency virus (HIV)-specific CD4(+) T cells is observed in...

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Main Authors: Iyasere, Christiana, Tilton, John C., Johnson, Alison J., Younes, Souheil, Yassine-Diab, Bader, Sekaly, Rafick-Pierre, Kwok, William W., Migueles, Stephen A., Laborico, Alisha C., Shupert, W. Lesley, Hallahan, Claire W., Davey, Jr., Richard T., Dybul, Mark, Vogel, Susan, Metcalf, Julia, Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC224997/
https://ncbi.nlm.nih.gov/pubmed/14512540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.20.10900-10909.2003
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