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High-level HIV-1 viremia suppresses viral antigen-specific CD4(+) T cell proliferation

In chronic viral infections of humans and experimental animals, virus-specific CD4(+) T cell function is believed to be critical for induction and maintenance of host immunity that mediates effective restriction of viral replication. Because in vitro proliferation of HIV-specific memory CD4(+) T cel...

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Detalhes bibliográficos
Main Authors: McNeil, Andrew C., Shupert, W. Lesley, Iyasere, Christiana A., Hallahan, Claire W., Mican, JoAnn, Davey, Richard T., Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC61135/
https://ncbi.nlm.nih.gov/pubmed/11717444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251539598
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