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EVM005: An Ectromelia-Encoded Protein with Dual Roles in NF-κB Inhibition and Virulence
Poxviruses contain large dsDNA genomes encoding numerous open reading frames that manipulate cellular signalling pathways and interfere with the host immune response. The NF-κB signalling cascade is an important mediator of innate immunity and inflammation, and is tightly regulated by ubiquitination...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133408/ https://ncbi.nlm.nih.gov/pubmed/25122471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004326 |
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