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Polypeptides derived from α-Synuclein binding partners to prevent α-Synuclein fibrils interaction with and take-up by cells

α-Synuclein (αSyn) fibrils spread from one neuronal cell to another. This prion-like phenomenon is believed to contribute to the progression of the pathology in Parkinson’s disease and other synucleinopathies. The binding of αSyn fibrils originating from affected cells to the plasma membrane of naïv...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Monsellier, Elodie, Bendifallah, Maya, Redeker, Virginie, Melki, Ronald
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425896/
https://ncbi.nlm.nih.gov/pubmed/32790707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237328
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