Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer

Steroidogenic enzymes are crucial in prostate cancer (PCa) progression. 17β-Hydroxysteroid dehydrogenase type 4 (HSD17B4), encoded by HSD17B4, lacks catalytic capacity in androgen metabolism. Now the detailed role and molecular mechanism of PCa development are largely unknown. Here we showed that th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Huang, Huichao, Liu, Ruijie, Huang, Yahui, Feng, Yilu, Fu, Ying, Chen, Lin, Chen, Zhuchu, Cai, Yi, Zhang, Ye, Chen, Yongheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425433/
https://ncbi.nlm.nih.gov/pubmed/32678070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103530
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