Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer

Steroidogenic enzymes are crucial in prostate cancer (PCa) progression. 17β-Hydroxysteroid dehydrogenase type 4 (HSD17B4), encoded by HSD17B4, lacks catalytic capacity in androgen metabolism. Now the detailed role and molecular mechanism of PCa development are largely unknown. Here we showed that th...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Huang, Huichao, Liu, Ruijie, Huang, Yahui, Feng, Yilu, Fu, Ying, Chen, Lin, Chen, Zhuchu, Cai, Yi, Zhang, Ye, Chen, Yongheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7425433/
https://ncbi.nlm.nih.gov/pubmed/32678070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103530
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