Functional silencing of HSD17B2 in prostate cancer promotes disease progression

PURPOSE: Steroidogenic enzymes are essential for prostate cancer development. Enzymes inactivating potent androgens were not investigated thoroughly, which leads to limited interfere strategies for prostate cancer therapy. Here we characterized the clinical relevance, significance and regulation mec...

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Bibliografski detalji
Izdano u:Clin Cancer Res
Glavni autori: Gao, Xiaomei, Dai, Charles, Huang, Shengsong, Tang, Jingjie, Chen, Guoyuan, Li, Jianneng, Zhu, Ziqi, Zhu, Xuyou, Zhou, Shuirong, Gao, Yuanyuan, Hou, Zemin, Fang, Zijun, Xu, Chengdang, Wang, Jianyang, Wu, Denglong, Sharifi, Nima, Li, Zhenfei
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377858/
https://ncbi.nlm.nih.gov/pubmed/30228209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2392
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