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Functional silencing of HSD17B2 in prostate cancer promotes disease progression

PURPOSE: Steroidogenic enzymes are essential for prostate cancer development. Enzymes inactivating potent androgens were not investigated thoroughly, which leads to limited interfere strategies for prostate cancer therapy. Here we characterized the clinical relevance, significance and regulation mec...

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Podrobná bibliografie
Vydáno v:Clin Cancer Res
Hlavní autoři: Gao, Xiaomei, Dai, Charles, Huang, Shengsong, Tang, Jingjie, Chen, Guoyuan, Li, Jianneng, Zhu, Ziqi, Zhu, Xuyou, Zhou, Shuirong, Gao, Yuanyuan, Hou, Zemin, Fang, Zijun, Xu, Chengdang, Wang, Jianyang, Wu, Denglong, Sharifi, Nima, Li, Zhenfei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377858/
https://ncbi.nlm.nih.gov/pubmed/30228209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2392
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